Cheapest way to kill the sound?
Toss the keys on the counter and leave them there. (quiet and cheap

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How much sound are we trying to kill? Flowmasters and turndowns under the truck and trying to make it as quiet as a new Caddy? Wind noise? Nagging other?
Seriously, I used peel and seal type stuff, repaired sheetmetal (includes any cracked welds etc) new weather strip, made sure doors and glass were aligned properly. A lot of little noises can add up to a lot of racket.
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'86 C-30 dually, 454/tbh400
'73 K-20 350/350/205 (sold

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I'm kinda like duct tape- no real purpose, but handy to have around.