fuel plumbing

[hardhead]

I'm about to install a 6.0 truck motor in my son's 66 and I have a few questions. Can I just plug the fuel rail return and run only a supply line with a vette fiter/reg ? If I can do this, what will I need ? supply hose from tank to a pre filter, pump, and the vette regulator with return to the tank ? Is rubber ok as long as it is upsteam of the pump ? Where is the best place to buy high pressure hose for downstream of the pump ? I have some free 1/2" SS tubing I am planning on using for the hard line.